Fenox

Composition

Fenox tablet: Each film coated tablet contains Fexofenadine Hydrochloride USP 120 mg.

Pharmacology

Fexofenadine Hydrochloride is an antihistamine with selective peripheral H1-receptor antagonist activity. This leads to relief of the allergic symptoms. Unlike most other antihistamines, Fexofenadine does not cross Blood Brain Barrier, and therefore, does not cause drowsiness.

Indication

  • Seasonal Allergic Rhinitis
  • Chronic Idiopathic Urticaria

Dosage and Administration

Seasonal Allergic Rhinitis and Chronic Idiopathic Urticaria: Adults and Children > 12 years: 60 mg (1/2 tablet) twice daily or 120 mg (1 tablet) once daily or 180 mg (1.5 tablet) once daily with water.

Children 6 to 11 years: 30 mg twice daily.

Use in Pregnancy & Lactation

There is no adequate and well controlled study in pregnant women. Fexofenadine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Fexofenadine is excreted in human milk or not. Caution should be exercised when Fexofenadine is administered to a nursing woman.

Side Effect

Fexofenadine is generally well tolerated. The most commonly reported adverse events are headache, nausea and dizziness.

Contraindication

Fexofenadine is contraindicated in patients with known hypersensitivity to any of the ingredients.

Drug Interaction

Plasma concentrations of Fexofenadine have been increased when given with Erythromycin or Ketoconazole. Antacid containing Aluminium and Magnesium Hydroxide reduces the absorption of Fexofenadine. Fruit juices including grape fruit may reduce the bioavailability of Fexofenadine and use together should be avoided.

Storage

Keep out of the reach of children. Keep below 30°C, protect from light.

How Supplied

Fenox tablet: Each box contains 3x10’s tablet in blister pack.